A long-lasting protective immunity against chronic toxoplasmosis in mice induced by recombinant rhoptry proteins encapsulated in poly (lactide-co-glycolide) microparticles.

Xu, Ying; Zhang, Nian-Zhang; Wang, Meng; Dong, Hu; Feng, Sheng-Yong; Guo, Hui-Chen; Zhu, Xing-Quan

Xu, Ying; Zhang, Nian-Zhang; Wang, Meng; Dong, Hu; Feng, Sheng-Yong; Guo, Hui-Chen; Zhu, Xing-Quan.

Afiliação

Xu Y; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.
Zhang NZ; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Protozoa Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, People's Republic of China.
Wang M; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.
Dong H; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.
Feng SY; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.
Guo HC; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China.
Zhu XQ; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, 730046, People's Republic of China. guohuichen@caas.cn.

Parasitol Res ; 114(11): 4195-203, 2015 Nov.

Article em En | MEDLINE | ID: mdl-26243574

Assuntos

Antígenos de Protozoários/administração & dosagem; Antígenos de Protozoários/imunologia; Proteínas de Protozoários/administração & dosagem; Vacinas Protozoárias/imunologia; Toxoplasma/imunologia; Toxoplasmose Animal/imunologia; Animais; Anticorpos Antiprotozoários/sangue; Portadores de Fármacos/administração & dosagem; Feminino; Humanos; Imunização; Camundongos; Modelos Animais; Poliésteres/administração & dosagem; Proteínas de Protozoários/imunologia; Proteínas Recombinantes; Toxoplasmose Animal/prevenção & controle

Palavras-chave

Poly (lactide-co-glycolide) microparticles; Protective immunity; Rhoptry protein 18; Rhoptry protein 38; Toxoplasma gondii; Toxoplasmosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Toxoplasma / Proteínas de Protozoários / Toxoplasmose Animal / Vacinas Protozoárias / Antígenos de Protozoários Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Parasitol Res Assunto da revista: PARASITOLOGIA Ano de publicação: 2015 Tipo de documento: Article

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