Micrometer-sized network structure of novel DNA-lipid conjugates induced by heat stimulation.
Soft Matter
; 11(35): 7053-8, 2015 Sep 21.
Article
em En
| MEDLINE
| ID: mdl-26249035
ABSTRACT
We have developed a novel lipid-bearing DNA that forms hairpin modules, including a single RNA monomer; this can be used to create micrometer-sized structures from nanometer-sized building blocks during breakage at the RNA site. In the presence of divalent metal ions and heat stimulation, we observed transition of the self-assembly, which results in the formation of a three-dimensional network structure. To our knowledge, this is also the first report of heat-induced micrometer-sized molecular self-assembly of molecules that carry biological information.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA
/
Lipídeos
Idioma:
En
Revista:
Soft Matter
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Japão