The influence of the C5 substituent on the 2-thiouridine desulfuration pathway and the conformational analysis of the resulting 4-pyrimidinone products.

Bartos, Paulina; Ebenryter-Olbinska, Katarzyna; Sochacka, Elzbieta; Nawrot, Barbara

Bartos, Paulina; Ebenryter-Olbinska, Katarzyna; Sochacka, Elzbieta; Nawrot, Barbara.

Afiliação

Bartos P; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, Lodz, Poland.
Ebenryter-Olbinska K; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, Lodz, Poland.
Sochacka E; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, Lodz, Poland. Electronic address: elzbieta.sochacka@p.lodz.pl.
Nawrot B; Department of Bioorganic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland. Electronic address: bnawrot@cbmm.lodz.pl.

Bioorg Med Chem ; 23(17): 5587-94, 2015 Sep 01.

Article em En | MEDLINE | ID: mdl-26254829

Assuntos

Pirimidinonas/metabolismo; RNA de Transferência/química; Tiouridina/análogos & derivados; Humanos; Modelos Moleculares; Estresse Oxidativo; Tiouridina/metabolismo

Palavras-chave

2-Thiouridine; 4-Pyrimidinone riboside; Conformational analysis; Desulfuration; Oxidative stress; tRNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinonas / Tiouridina / RNA de Transferência Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Polônia

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