[Modern Nanomedicine in Treatment of Lung Carcinomas]. / Moderní nanomedicína v lécbe karcinomu plic.
Klin Onkol
; 28(4): 245-50, 2015.
Article
em Cs
| MEDLINE
| ID: mdl-26299737
ABSTRACT
BACKGROUNDS Despite the fast development of new effective cytostatics and targeted therapy, the treatment efficiency of lung cancer is still insufficient. The systemic administration of drugs results in a decrease in drug concentrations in tumor site, particularly due to specific extracellular environment in lungs. Nanotransporters could serve as a platform, protecting a drug against these undesired effects, which may enhance its therapeutic index and reduce side effects of a drug. Moreover, nanotechnologies possess the potential to improve the diagnostics of lung cancer, and thus increase a survival rate of oncologic patients. AIM:
The presented study is aimed to demonstrate the possibilities provided by nanotechnologies in the field of treatment and diagnostic of lung cancers and discuss the obstacles, which complicate a translation into clinical practice.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nanomedicina
/
Neoplasias Pulmonares
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
Cs
Revista:
Klin Onkol
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2015
Tipo de documento:
Article