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Comprehensive assessment of cancer missense mutation clustering in protein structures.
Kamburov, Atanas; Lawrence, Michael S; Polak, Paz; Leshchiner, Ignaty; Lage, Kasper; Golub, Todd R; Lander, Eric S; Getz, Gad.
Afiliação
  • Kamburov A; Department of Pathology and Cancer Center, Massachusetts General Hospital, Boston, MA 02114; Harvard Medical School, Boston, MA 02115; Broad Institute of MIT and Harvard, Cambridge, MA 02142;
  • Lawrence MS; Broad Institute of MIT and Harvard, Cambridge, MA 02142;
  • Polak P; Department of Pathology and Cancer Center, Massachusetts General Hospital, Boston, MA 02114; Harvard Medical School, Boston, MA 02115; Broad Institute of MIT and Harvard, Cambridge, MA 02142;
  • Leshchiner I; Broad Institute of MIT and Harvard, Cambridge, MA 02142;
  • Lage K; Harvard Medical School, Boston, MA 02115; Broad Institute of MIT and Harvard, Cambridge, MA 02142; Department of Surgery, Massachusetts General Hospital, Boston, MA 02114.
  • Golub TR; Broad Institute of MIT and Harvard, Cambridge, MA 02142;
  • Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA 02142; lander@broadinstitute.org gadgetz@broadinstitute.org.
  • Getz G; Department of Pathology and Cancer Center, Massachusetts General Hospital, Boston, MA 02114; Harvard Medical School, Boston, MA 02115; Broad Institute of MIT and Harvard, Cambridge, MA 02142; lander@broadinstitute.org gadgetz@broadinstitute.org.
Proc Natl Acad Sci U S A ; 112(40): E5486-95, 2015 Oct 06.
Article em En | MEDLINE | ID: mdl-26392535

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Oncogênicas / Mutação de Sentido Incorreto / Neoplasias Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Oncogênicas / Mutação de Sentido Incorreto / Neoplasias Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2015 Tipo de documento: Article