Selective oestrogen receptor modulators lasofoxifene and bazedoxifene inhibit joint inflammation and osteoporosis in ovariectomised mice with collagen-induced arthritis.

Andersson, Annica; Bernardi, Angelina I; Stubelius, Alexandra; Nurkkala-Karlsson, Merja; Ohlsson, Claes; Carlsten, Hans; Islander, Ulrika

Andersson, Annica; Bernardi, Angelina I; Stubelius, Alexandra; Nurkkala-Karlsson, Merja; Ohlsson, Claes; Carlsten, Hans; Islander, Ulrika.

Afiliação

Andersson A; Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research and annica.andersson@rheuma.gu.se.
Bernardi AI; Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research and.
Stubelius A; Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research and.
Nurkkala-Karlsson M; Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research and.
Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Carlsten H; Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research and.
Islander U; Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research and.

Rheumatology (Oxford) ; 55(3): 553-63, 2016 Mar.

Article em En | MEDLINE | ID: mdl-26424839

Assuntos

Artrite Experimental/tratamento farmacológico; Indóis/farmacologia; Osteoartrite/tratamento farmacológico; Osteoporose Pós-Menopausa/tratamento farmacológico; Pirrolidinas/farmacologia; Moduladores Seletivos de Receptor Estrogênico/farmacologia; Tetra-Hidronaftalenos/farmacologia; Animais; Área Sob a Curva; Artrite Experimental/patologia; Biomarcadores/sangue; Colágeno/farmacologia; Modelos Animais de Doenças; Feminino; Citometria de Fluxo; Humanos; Interleucina-6/sangue; Camundongos; Camundongos Endogâmicos DBA; Osteoartrite/induzido quimicamente; Osteoartrite/fisiopatologia; Osteoporose Pós-Menopausa/patologia; Ovariectomia/métodos; Distribuição Aleatória; Resultado do Tratamento

Palavras-chave

arthritis; oestrogen; osteoporosis; selective oestrogen receptor modulators

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Artrite Experimental / Pirrolidinas / Tetra-Hidronaftalenos / Osteoporose Pós-Menopausa / Moduladores Seletivos de Receptor Estrogênico / Indóis Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Rheumatology (Oxford) Assunto da revista: REUMATOLOGIA Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google