Tristetraprolin induces cell cycle arrest in breast tumor cells through targeting AP-1/c-Jun and NF-&#954;B pathway.

Xu, Li; Ning, Huan; Gu, Ling; Wang, Qinghong; Lu, Wenbao; Peng, Hui; Cui, Weiguang; Ying, Baoling; Ross, Christina R; Wilson, Gerald M; Wei, Lin; Wold, William S M; Liu, Jianguo

Tristetraprolin induces cell cycle arrest in breast tumor cells through targeting AP-1/c-Jun and NF-κB pathway.

Xu, Li; Ning, Huan; Gu, Ling; Wang, Qinghong; Lu, Wenbao; Peng, Hui; Cui, Weiguang; Ying, Baoling; Ross, Christina R; Wilson, Gerald M; Wei, Lin; Wold, William S M; Liu, Jianguo.

Afiliação

Xu L; Department of Respiratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ning H; Division of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA.
Gu L; Division of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA.
Wang Q; Division of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA.
Lu W; Division of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA.
Peng H; Division of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA.
Cui W; Division of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA.
Ying B; Division of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA.
Ross CR; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Wilson GM; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.
Wei L; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.
Wold WS; Department of Immunology, School of Basic Medicine, Hebei Medical University, Shijiazhuang, Hebei, China.
Liu J; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.

Oncotarget ; 6(39): 41679-91, 2015 Dec 08.

Article em En | MEDLINE | ID: mdl-26497679

Assuntos

Neoplasias da Mama/metabolismo; Proteínas Proto-Oncogênicas c-jun/metabolismo; Pontos de Checagem da Fase S do Ciclo Celular; Fator de Transcrição AP-1/metabolismo; Fator de Transcrição RelA/metabolismo; Tristetraprolina/metabolismo; Animais; Neoplasias da Mama/genética; Neoplasias da Mama/patologia; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Proliferação de Células; Feminino; Regulação Neoplásica da Expressão Gênica; Células HEK293; Xenoenxertos; Humanos; Células MCF-7; Camundongos; Proteínas Nucleares/genética; Proteínas Nucleares/metabolismo; Proteínas Tirosina Quinases/genética; Proteínas Tirosina Quinases/metabolismo; Proteínas Proto-Oncogênicas c-jun/genética; Transdução de Sinais; Fatores de Tempo; Fator de Transcrição AP-1/genética; Fator de Transcrição RelA/genética; Transcrição Gênica; Transfecção; Tristetraprolina/genética; Carga Tumoral

Palavras-chave

AP-1; apoptosis; breast cancer; cell cycle; tristetraprolin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Proteínas Proto-Oncogênicas c-jun / Fator de Transcrição AP-1 / Fator de Transcrição RelA / Tristetraprolina / Pontos de Checagem da Fase S do Ciclo Celular Limite: Animals / Female / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

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