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Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.
Lafkas, Daniel; Shelton, Amy; Chiu, Cecilia; de Leon Boenig, Gladys; Chen, Yongmei; Stawicki, Scott S; Siltanen, Christian; Reichelt, Mike; Zhou, Meijuan; Wu, Xiumin; Eastham-Anderson, Jeffrey; Moore, Heather; Roose-Girma, Meron; Chinn, Yvonne; Hang, Julie Q; Warming, Søren; Egen, Jackson; Lee, Wyne P; Austin, Cary; Wu, Yan; Payandeh, Jian; Lowe, John B; Siebel, Christian W.
Afiliação
  • Lafkas D; Department of Discovery Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Shelton A; Department of Discovery Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Chiu C; Department of Antibody Engineering, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • de Leon Boenig G; Department of Structural Biology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Chen Y; Department of Antibody Engineering, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Stawicki SS; Department of Antibody Engineering, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Siltanen C; Department of Discovery Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Reichelt M; Department of Pathology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Zhou M; Department of Translational Immunology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Wu X; Department of Translational Immunology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Eastham-Anderson J; Department of Pathology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Moore H; Department of Discovery Immunology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Roose-Girma M; Department of Molecular Biology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Chinn Y; Departments of Protein Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Hang JQ; Departments of Protein Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Warming S; Department of Molecular Biology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Egen J; Department of Discovery Immunology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Lee WP; Department of Translational Immunology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Austin C; Department of Pathology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Wu Y; Department of Antibody Engineering, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Payandeh J; Department of Structural Biology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Lowe JB; Department of Pathology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Siebel CW; Department of Discovery Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
Nature ; 528(7580): 127-31, 2015 Dec 03.
Article em En | MEDLINE | ID: mdl-26580007
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Notch / Transdiferenciação Celular / Pulmão / Anticorpos Tipo de estudo: Prognostic_studies Idioma: En Revista: Nature Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Notch / Transdiferenciação Celular / Pulmão / Anticorpos Tipo de estudo: Prognostic_studies Idioma: En Revista: Nature Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos