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An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation.
Smit, Linda; Berns, Katrien; Spence, Katherine; Ryder, W David; Zeps, Nik; Madiredjo, Mandy; Beijersbergen, Roderick; Bernards, René; Clarke, Robert B.
Afiliação
  • Smit L; Division of Molecular Carcinogenesis and Cancer Genomics Center Netherlands, The Netherlands Cancer Institute, Plesmanlaan, CX, Amsterdam, The Netherlands.
  • Berns K; Department of Hematology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan, Amsterdam, The Netherlands.
  • Spence K; Division of Molecular Carcinogenesis and Cancer Genomics Center Netherlands, The Netherlands Cancer Institute, Plesmanlaan, CX, Amsterdam, The Netherlands.
  • Ryder WD; Breast Biology Group, Breast Cancer Now Research Unit, Institute of Cancer Sciences, University of Manchester, Manchester, UK.
  • Zeps N; Department of Medical Statistics, The Christie NHS Trust, Manchester, UK.
  • Madiredjo M; St John of God Subiaco Hospital, Subiaco, Perth, WA, Australia.
  • Beijersbergen R; Division of Molecular Carcinogenesis and Cancer Genomics Center Netherlands, The Netherlands Cancer Institute, Plesmanlaan, CX, Amsterdam, The Netherlands.
  • Bernards R; Division of Molecular Carcinogenesis and Cancer Genomics Center Netherlands, The Netherlands Cancer Institute, Plesmanlaan, CX, Amsterdam, The Netherlands.
  • Clarke RB; Division of Molecular Carcinogenesis and Cancer Genomics Center Netherlands, The Netherlands Cancer Institute, Plesmanlaan, CX, Amsterdam, The Netherlands.
Oncotarget ; 7(3): 2596-610, 2016 Jan 19.
Article em En | MEDLINE | ID: mdl-26595803

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias da Mama / Transformação Celular Neoplásica / Fosfatidilinositol 3-Quinases / Glândulas Mamárias Humanas / Proteínas Proto-Oncogênicas c-akt / Proteína Forkhead Box O3 Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias da Mama / Transformação Celular Neoplásica / Fosfatidilinositol 3-Quinases / Glândulas Mamárias Humanas / Proteínas Proto-Oncogênicas c-akt / Proteína Forkhead Box O3 Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda