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Pharmacological perspectives in sarcopenia: a potential role for renin-angiotensin system blockers?
Sartiani, Laura; Spinelli, Valentina; Laurino, Annunziatina; Blescia, Sabrina; Raimondi, Laura; Cerbai, Elisabetta; Mugelli, Alessandro.
Afiliação
  • Sartiani L; Department of Neurosciences, Psychology, Drug Research and Child Health (NeuroFarBa), Center of Molecular Medicine (CIMMBA), University of Florence, Florence, Italy.
  • Spinelli V; Department of Neurosciences, Psychology, Drug Research and Child Health (NeuroFarBa), Center of Molecular Medicine (CIMMBA), University of Florence, Florence, Italy.
  • Laurino A; Department of Neurosciences, Psychology, Drug Research and Child Health (NeuroFarBa), Center of Molecular Medicine (CIMMBA), University of Florence, Florence, Italy.
  • Blescia S; Department of Neurosciences, Psychology, Drug Research and Child Health (NeuroFarBa), Center of Molecular Medicine (CIMMBA), University of Florence, Florence, Italy.
  • Raimondi L; Department of Neurosciences, Psychology, Drug Research and Child Health (NeuroFarBa), Center of Molecular Medicine (CIMMBA), University of Florence, Florence, Italy.
  • Cerbai E; Department of Neurosciences, Psychology, Drug Research and Child Health (NeuroFarBa), Center of Molecular Medicine (CIMMBA), University of Florence, Florence, Italy.
  • Mugelli A; Department of Neurosciences, Psychology, Drug Research and Child Health (NeuroFarBa), Center of Molecular Medicine (CIMMBA), University of Florence, Florence, Italy.
Clin Cases Miner Bone Metab ; 12(2): 135-8, 2015.
Article em En | MEDLINE | ID: mdl-26604938
ABSTRACT
Sarcopenia represents a major health problem highly prevalent in elderly and age-related chronic diseases. Current pharmacological strategies available to prevent and reverse sarcopenia are largely unsatisfactory thus raising the need to identify novel targets for pharmacological intervention and possibly more effective and safe drugs. This review highlights the current knowledge of the potential benefits of renin-angiotensin system blockade in sarcopenia and discuss the main mechanisms underlying the effects.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Cases Miner Bone Metab Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Cases Miner Bone Metab Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Itália