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UGT1A1 genotype-dependent dose adjustment of belinostat in patients with advanced cancers using population pharmacokinetic modeling and simulation.
Peer, Cody J; Goey, Andrew K L; Sissung, Tristan M; Erlich, Sheryl; Lee, Min-Jung; Tomita, Yusuke; Trepel, Jane B; Piekarz, Richard; Balasubramaniam, Sanjeeve; Bates, Susan E; Figg, William D.
Afiliação
  • Peer CJ; Clinical Pharmacology Program, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Goey AK; Clinical Pharmacology Program, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Sissung TM; Clinical Pharmacology Program, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Erlich S; Clinical Pharmacology Program, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Lee MJ; Developmental Therapeutics Branch, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Tomita Y; Developmental Therapeutics Branch, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Trepel JB; Developmental Therapeutics Branch, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Piekarz R; Cancer Therapy Evaluation Program, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Balasubramaniam S; Developmental Therapeutics Branch, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Bates SE; Developmental Therapeutics Branch, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Figg WD; Clinical Pharmacology Program, National Cancer Institute, NIH, Bethesda, MD, USA.
J Clin Pharmacol ; 56(4): 450-60, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26637161
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Glucuronosiltransferase / Ácidos Hidroxâmicos / Neoplasias / Antineoplásicos Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Pharmacol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Glucuronosiltransferase / Ácidos Hidroxâmicos / Neoplasias / Antineoplásicos Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Pharmacol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos