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PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically.
Dickey, Audrey S; Pineda, Victor V; Tsunemi, Taiji; Liu, Patrick P; Miranda, Helen C; Gilmore-Hall, Stephen K; Lomas, Nicole; Sampat, Kunal R; Buttgereit, Anne; Torres, Mark-Joseph Manalang; Flores, April L; Arreola, Martin; Arbez, Nicolas; Akimov, Sergey S; Gaasterland, Terry; Lazarowski, Eduardo R; Ross, Christopher A; Yeo, Gene W; Sopher, Bryce L; Magnuson, Gavin K; Pinkerton, Anthony B; Masliah, Eliezer; La Spada, Albert R.
Afiliação
  • Dickey AS; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
  • Pineda VV; Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
  • Tsunemi T; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
  • Liu PP; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA.
  • Miranda HC; Institute for Genomic Medicine, University of California San Diego, La Jolla, California, USA.
  • Gilmore-Hall SK; Sanford Consortium for Regenerative Medicine, University of California San Diego, La Jolla, California, USA.
  • Lomas N; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
  • Sampat KR; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
  • Buttgereit A; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
  • Torres MJ; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
  • Flores AL; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
  • Arreola M; Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
  • Arbez N; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
  • Akimov SS; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
  • Gaasterland T; Division of Neurobiology, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Lazarowski ER; Division of Neurobiology, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Ross CA; Sanford Consortium for Regenerative Medicine, University of California San Diego, La Jolla, California, USA.
  • Yeo GW; Scripps Institute for Oceanography, University of California San Diego, La Jolla, California, USA.
  • Sopher BL; Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
  • Magnuson GK; Division of Neurobiology, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Pinkerton AB; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Masliah E; Department of Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • La Spada AR; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Nat Med ; 22(1): 37-45, 2016 Jan.
Article em En | MEDLINE | ID: mdl-26642438
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neostriado / Doença de Huntington / Receptores Citoplasmáticos e Nucleares / Proteínas do Tecido Nervoso / Neurônios Limite: Animals / Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neostriado / Doença de Huntington / Receptores Citoplasmáticos e Nucleares / Proteínas do Tecido Nervoso / Neurônios Limite: Animals / Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos