Ambient-Temperature Newman-Kwart Rearrangement Mediated by Organic Photoredox Catalysis.
J Am Chem Soc
; 137(50): 15684-7, 2015 Dec 23.
Article
em En
| MEDLINE
| ID: mdl-26645387
ABSTRACT
The Newman-Kwart rearrangement is perhaps the quintessential method for the synthesis of thiophenols from the corresponding phenol. However, the high thermal conditions required for the rearrangement of the requisite O-aryl carbamothioates often leads to decomposition. Herein, we present a general strategy for catalysis of O-aryl carbamothioates to S-aryl carbamothioates using catalytic quantities of a commercially available organic single-electron photooxidant. Importantly, this reaction is facilitated at ambient temperatures.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Am Chem Soc
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Estados Unidos