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Treatment with the HIV protease inhibitor nelfinavir triggers the unfolded protein response and may overcome proteasome inhibitor resistance of multiple myeloma in combination with bortezomib: a phase I trial (SAKK 65/08).
Driessen, Christoph; Kraus, Marianne; Joerger, Markus; Rosing, Hilde; Bader, Jürgen; Hitz, Felicitas; Berset, Catherine; Xyrafas, Alexandros; Hawle, Hanne; Berthod, Gregoire; Overkleeft, Hermann S; Sessa, Christiana; Huitema, Alwin; Pabst, Thomas; von Moos, Roger; Hess, Dagmar; Mey, Ulrich J M.
Afiliação
  • Driessen C; Department of Oncology/Hematology, Kantonsspital St. Gallen, Switzerland christoph.driessen@kssg.ch.
  • Kraus M; Department of Oncology/Hematology, Kantonsspital St. Gallen, Switzerland.
  • Joerger M; Department of Oncology/Hematology, Kantonsspital St. Gallen, Switzerland.
  • Rosing H; Slotervaart Hospital/The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Bader J; Department of Oncology/Hematology, Kantonsspital St. Gallen, Switzerland.
  • Hitz F; Department of Oncology/Hematology, Kantonsspital St. Gallen, Switzerland.
  • Berset C; SAKK Coordinating Center, Bern, Switzerland.
  • Xyrafas A; SAKK Coordinating Center, Bern, Switzerland.
  • Hawle H; SAKK Coordinating Center, Bern, Switzerland.
  • Berthod G; University Hospital CHUV, Lausanne, Switzerland.
  • Overkleeft HS; University of Leiden, the Netherlands.
  • Sessa C; San Giovanni hospital, Bellinzona, Switzerland.
  • Huitema A; Slotervaart Hospital/The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Pabst T; Department of Medical Oncology, Inselspital, University Hospital and University of Bern, Switzerland.
  • von Moos R; Hematology & Medical Oncology, Kantonsspital Graubuenden, Chur, Switzerland.
  • Hess D; Department of Oncology/Hematology, Kantonsspital St. Gallen, Switzerland.
  • Mey UJ; Hematology & Medical Oncology, Kantonsspital Graubuenden, Chur, Switzerland.
Haematologica ; 101(3): 346-55, 2016 Mar.
Article em En | MEDLINE | ID: mdl-26659919
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia / Protocolos de Quimioterapia Combinada Antineoplásica / Nelfinavir / Bortezomib / Linfoma / Mieloma Múltiplo Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Haematologica Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia / Protocolos de Quimioterapia Combinada Antineoplásica / Nelfinavir / Bortezomib / Linfoma / Mieloma Múltiplo Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Haematologica Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça