Your browser doesn't support javascript.
loading
Early- and late-stage ocular complications of herpes zoster ophthalmicus in rural South Africa.
Schaftenaar, Erik; Meenken, Christina; Baarsma, G Seerp; McIntyre, James A; Verjans, Georges M G M; Peters, Remco P H.
Afiliação
  • Schaftenaar E; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Meenken C; Rotterdam Eye Hospital, Rotterdam, The Netherlands.
  • Baarsma GS; Anova Health Institute, Johannesburg and Tzaneen, South Africa.
  • McIntyre JA; Department of Ophthalmology, VU University Medical Center, Amsterdam, The Netherlands.
  • Verjans GM; Rotterdam Eye Hospital, Rotterdam, The Netherlands.
  • Peters RP; Rotterdam Ophthalmic Institute, Rotterdam, The Netherlands.
Trop Med Int Health ; 21(3): 334-9, 2016 Mar.
Article em En | MEDLINE | ID: mdl-26663773
ABSTRACT

OBJECTIVES:

To describe the spectrum of ocular complications of herpes zoster ophthalmicus (HZO) in rural South Africa.

METHODS:

Patients presenting with visual complaints and active or healed HZO at the ophthalmology outpatient department of three hospitals in rural South Africa were included in this study. Demographic and clinical data were collected, and HIV status was determined for all participants.

RESULTS:

Forty-eight patients were included, and 81% were HIV infected. Poor vision was reported by 94% of patients, painful eye by 79% and photophobia by 63%. A diverse spectrum of ocular complications was observed with corneal inflammation and opacification in 77% followed by anterior uveitis in 65%. The majority (65%) presented with late-stage ocular complications associated with irreversible loss of vision whereas early-stage complications, such as punctate epithelial keratitis and anterior uveitis, were less common. Blindness of the affected eye was observed in 68% of patients with late-stage complications. There was a considerable delay between onset of symptoms and first presentation to the ophthalmology outpatient department (median time 35 days; range 1-2500 days), and longer delay was associated with late-stage ocular complications (P = 0.02).

CONCLUSIONS:

HZO patients present with relatively late-stage ocular complications, and blindness among these patients is common. The delayed presentation to the ophthalmology outpatient department of hospitals in our rural setting is of concern, and efforts to improve ocular outcomes of HZO are urgently needed.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Herpes Zoster Oftálmico Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Africa Idioma: En Revista: Trop Med Int Health Assunto da revista: MEDICINA TROPICAL / SAUDE PUBLICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Herpes Zoster Oftálmico Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Africa Idioma: En Revista: Trop Med Int Health Assunto da revista: MEDICINA TROPICAL / SAUDE PUBLICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda