Microscopic Plasmodium falciparum Gametocytemia and Infectivity to Mosquitoes in Cambodia.
J Infect Dis
; 213(9): 1491-4, 2016 May 01.
Article
em En
| MEDLINE
| ID: mdl-26667316
ABSTRACT
Although gametocytes are essential for malaria transmission, in Africa many falciparum-infected persons without smear-detectable gametocytes still infect mosquitoes. To see whether the same is true in Southeast Asia, we determined the infectiousness of 119 falciparum-infected Cambodian adults to Anopheles dirus mosquitoes by membrane feeding. Just 5.9% of subjects infected mosquitoes. The 8.4% of patients with smear-detectable gametocytes were >20 times more likely to infect mosquitoes than those without and were the source of 96% of all mosquito infections. In low-transmission settings, targeting transmission-blocking interventions to those with microscopic gametocytemia may have an outsized effect on malaria control and elimination.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmodium falciparum
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Malária Falciparum
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Parasitemia
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Insetos Vetores
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Anopheles
Limite:
Adolescent
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Adult
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Aged
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Animals
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Female
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Humans
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Middle aged
Idioma:
En
Revista:
J Infect Dis
Ano de publicação:
2016
Tipo de documento:
Article