Polymorphisms in Wnt signaling pathway genes are associated with peak bone mineral density, lean mass, and fat mass in Chinese male nuclear families.

Zheng, Y; Wang, C; Zhang, H; Shao, C; Gao, L-H; Li, S-S; Yu, W-J; He, J-W; Fu, W-Z; Hu, Y-Q; Li, M; Liu, Y-J; Zhang, Z-L

Zheng, Y; Wang, C; Zhang, H; Shao, C; Gao, L-H; Li, S-S; Yu, W-J; He, J-W; Fu, W-Z; Hu, Y-Q; Li, M; Liu, Y-J; Zhang, Z-L.

Afiliação

Zheng Y; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Wang C; Department of Endocrinology, Yueqing Hospital Affiliated with Wenzhou Medical University, 318 Qing-Yuan Road, Yueqing, Zhejiang, 325600, People's Republic of China.
Zhang H; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Shao C; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Gao LH; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Li SS; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Yu WJ; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
He JW; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Fu WZ; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Hu YQ; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Li M; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Liu YJ; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Zhang ZL; Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.

Osteoporos Int ; 27(5): 1805-15, 2016 May.

Article em En | MEDLINE | ID: mdl-26733379

Assuntos

Povo Asiático/genética; Composição Corporal/genética; Densidade Óssea/genética; Polimorfismo de Nucleotídeo Único; Via de Sinalização Wnt/genética; Absorciometria de Fóton/métodos; Adulto; Idoso; Composição Corporal/fisiologia; Índice de Massa Corporal; Densidade Óssea/fisiologia; Feminino; Colo do Fêmur/fisiologia; Estudos de Associação Genética; Genótipo; Haplótipos; Humanos; Desequilíbrio de Ligação; Vértebras Lombares/fisiologia; Masculino; Pessoa de Meia-Idade; Núcleo Familiar; Via de Sinalização Wnt/fisiologia

Palavras-chave

Body composition; Bone mineral density; Quantitative transmission disequilibrium test (QTDT); SNPs; Wnt pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Composição Corporal / Densidade Óssea / Polimorfismo de Nucleotídeo Único / Povo Asiático / Via de Sinalização Wnt Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Osteoporos Int Assunto da revista: METABOLISMO / ORTOPEDIA Ano de publicação: 2016 Tipo de documento: Article

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