Quantitative Secretomic Analysis Identifies Extracellular Protein Factors That Modulate the Metastatic Phenotype of Non-Small Cell Lung Cancer.

Hu, Rongkuan; Huffman, Kenneth E; Chu, Michael; Zhang, Yajie; Minna, John D; Yu, Yonghao

Hu, Rongkuan; Huffman, Kenneth E; Chu, Michael; Zhang, Yajie; Minna, John D; Yu, Yonghao.

Afiliação

Hu R; Department of Biochemistry and Hamon Center for Therapeutic Oncology Research, Simmons Comprehensive Cancer Center, Pharmacology and Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas 75235, United States.
Huffman KE; Department of Biochemistry and Hamon Center for Therapeutic Oncology Research, Simmons Comprehensive Cancer Center, Pharmacology and Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas 75235, United States.
Chu M; Department of Biochemistry and Hamon Center for Therapeutic Oncology Research, Simmons Comprehensive Cancer Center, Pharmacology and Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas 75235, United States.
Zhang Y; Department of Biochemistry and Hamon Center for Therapeutic Oncology Research, Simmons Comprehensive Cancer Center, Pharmacology and Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas 75235, United States.
Minna JD; Department of Biochemistry and Hamon Center for Therapeutic Oncology Research, Simmons Comprehensive Cancer Center, Pharmacology and Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas 75235, United States.
Yu Y; Department of Biochemistry and Hamon Center for Therapeutic Oncology Research, Simmons Comprehensive Cancer Center, Pharmacology and Internal Medicine, University of Texas Southwestern Medical Center , Dallas, Texas 75235, United States.

J Proteome Res ; 15(2): 477-86, 2016 Feb 05.

Article em En | MEDLINE | ID: mdl-26736068

Assuntos

Biomarcadores Tumorais/metabolismo; Espaço Extracelular/metabolismo; Proteoma/metabolismo; Proteômica/métodos; Biomarcadores Tumorais/genética; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/metabolismo; Carcinoma Pulmonar de Células não Pequenas/patologia; Linhagem Celular Transformada; Linhagem Celular Tumoral; Movimento Celular; Cromatografia Líquida; Regulação Neoplásica da Expressão Gênica; Ontologia Genética; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patologia; Metástase Neoplásica; Fenótipo; Prognóstico; Proteoma/genética; Interferência de RNA; RNA Interferente Pequeno/genética; Espectrometria de Massas em Tandem; Transfecção

Palavras-chave

metastasis; non-small cell lung cancer; proteomics and mass spectrometry; secretome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Proteoma / Proteômica / Espaço Extracelular Tipo de estudo: Prognostic_studies / Screening_studies Limite: Humans Idioma: En Revista: J Proteome Res Assunto da revista: BIOQUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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