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CYP1B1 inhibition attenuates doxorubicin-induced cardiotoxicity through a mid-chain HETEs-dependent mechanism.
Maayah, Zaid H; Althurwi, Hassan N; Abdelhamid, Ghada; Lesyk, Gabriela; Jurasz, Paul; El-Kadi, Ayman O S.
Afiliação
  • Maayah ZH; Faculty of Pharmacy & Pharmaceutical Sciences, Katz Group-Rexall Centre for Pharmacy and Health Research, T6G 2E1, University of Alberta, Edmonton, Canada.
  • Althurwi HN; Faculty of Pharmacy & Pharmaceutical Sciences, Katz Group-Rexall Centre for Pharmacy and Health Research, T6G 2E1, University of Alberta, Edmonton, Canada.
  • Abdelhamid G; Faculty of Pharmacy & Pharmaceutical Sciences, Katz Group-Rexall Centre for Pharmacy and Health Research, T6G 2E1, University of Alberta, Edmonton, Canada; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Helwan University, Egypt.
  • Lesyk G; Faculty of Pharmacy & Pharmaceutical Sciences, Katz Group-Rexall Centre for Pharmacy and Health Research, T6G 2E1, University of Alberta, Edmonton, Canada.
  • Jurasz P; Faculty of Pharmacy & Pharmaceutical Sciences, Katz Group-Rexall Centre for Pharmacy and Health Research, T6G 2E1, University of Alberta, Edmonton, Canada.
  • El-Kadi AO; Faculty of Pharmacy & Pharmaceutical Sciences, Katz Group-Rexall Centre for Pharmacy and Health Research, T6G 2E1, University of Alberta, Edmonton, Canada. Electronic address: aelkadi@ualberta.ca.
Pharmacol Res ; 105: 28-43, 2016 Mar.
Article em En | MEDLINE | ID: mdl-26772815
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estilbenos / Doxorrubicina / Ácidos Hidroxieicosatetraenoicos / Inibidores Enzimáticos / Cardiotoxicidade / Citocromo P-450 CYP1B1 / Antibióticos Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estilbenos / Doxorrubicina / Ácidos Hidroxieicosatetraenoicos / Inibidores Enzimáticos / Cardiotoxicidade / Citocromo P-450 CYP1B1 / Antibióticos Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Canadá