Primary signet ring cell carcinoma of the cervix: A case report and review of the literature.
Int J Surg Case Rep
; 21: 1-5, 2016.
Article
em En
| MEDLINE
| ID: mdl-26874582
ABSTRACT
INTRODUCTION:
Primary signet cell carcinoma of the cervix has been reported only in 18 cases to date. PRESENTATION OF CASE A 48-year-old woman was seen at our Gynecologic Oncology Unit, because she complained postcoital bleeding during the last three months. She had 1-2 cm cervical mass, originating from the endocervical canal. A biopsy revealed a signet ring cell-type adenocarcinoma. Suspected primary sites were excluded after gastroscopy, colonoscopy and mammography. The patient underwent a laparoscopic type-3 radical hysterectomy with bilateral salpingo-oophorectomy, pelvic lymph node dissection and paraaortic lymph node dissection with a presumed diagnosis of primary signet ring cell carcinoma of the cervix. Microscopically, the tumour consisted of 70% signet ring cell type and 30% endocervical adenocarcinoma. She did not receive any adjuvant treatment. Follow-up at 18 months after surgery showed no evidence of recurrence.DISCUSSION:
Nineteenth case of a primary signet ring cell carcinoma of the cervix was presented. Immunohistochemical studies and HPV DNA positivity may help in diagnosis.CONCLUSION:
It is crucial to differentiate primary tumour from metastatic signet cell carcinoma, while treatment and prognosis differ significantly.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Int J Surg Case Rep
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Turquia