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Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.
Mackenzie, Karen J; Carroll, Paula; Lettice, Laura; Tarnauskaite, Zygimante; Reddy, Kaalak; Dix, Flora; Revuelta, Ailsa; Abbondati, Erika; Rigby, Rachel E; Rabe, Björn; Kilanowski, Fiona; Grimes, Graeme; Fluteau, Adeline; Devenney, Paul S; Hill, Robert E; Reijns, Martin Am; Jackson, Andrew P.
Afiliação
  • Mackenzie KJ; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Carroll P; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Lettice L; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Tarnauskaite Z; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Reddy K; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Dix F; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Revuelta A; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Abbondati E; Roslin Institute, The University of Edinburgh, Edinburgh, UK.
  • Rigby RE; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Rabe B; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Kilanowski F; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Grimes G; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Fluteau A; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Devenney PS; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Hill RE; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Reijns MA; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.
  • Jackson AP; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK andrew.jackson@igmm.ed.ac.uk.
EMBO J ; 35(8): 831-44, 2016 Apr 15.
Article em En | MEDLINE | ID: mdl-26903602
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleases / Ribonuclease H / Mutação de Sentido Incorreto / Doenças Autoimunes do Sistema Nervoso / Imunidade Inata / Proteínas de Membrana / Malformações do Sistema Nervoso / Nucleotidiltransferases Limite: Animals / Humans Idioma: En Revista: EMBO J Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleases / Ribonuclease H / Mutação de Sentido Incorreto / Doenças Autoimunes do Sistema Nervoso / Imunidade Inata / Proteínas de Membrana / Malformações do Sistema Nervoso / Nucleotidiltransferases Limite: Animals / Humans Idioma: En Revista: EMBO J Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido