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Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.
Dunning, Alison M; Michailidou, Kyriaki; Kuchenbaecker, Karoline B; Thompson, Deborah; French, Juliet D; Beesley, Jonathan; Healey, Catherine S; Kar, Siddhartha; Pooley, Karen A; Lopez-Knowles, Elena; Dicks, Ed; Barrowdale, Daniel; Sinnott-Armstrong, Nicholas A; Sallari, Richard C; Hillman, Kristine M; Kaufmann, Susanne; Sivakumaran, Haran; Moradi Marjaneh, Mahdi; Lee, Jason S; Hills, Margaret; Jarosz, Monika; Drury, Suzie; Canisius, Sander; Bolla, Manjeet K; Dennis, Joe; Wang, Qin; Hopper, John L; Southey, Melissa C; Broeks, Annegien; Schmidt, Marjanka K; Lophatananon, Artitaya; Muir, Kenneth; Beckmann, Matthias W; Fasching, Peter A; Dos-Santos-Silva, Isabel; Peto, Julian; Sawyer, Elinor J; Tomlinson, Ian; Burwinkel, Barbara; Marme, Frederik; Guénel, Pascal; Truong, Thérèse; Bojesen, Stig E; Flyger, Henrik; González-Neira, Anna; Perez, Jose I A; Anton-Culver, Hoda; Eunjung, Lee; Arndt, Volker; Brenner, Hermann.
Afiliação
  • Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Thompson D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • French JD; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Beesley J; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Healey CS; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Kar S; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Pooley KA; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Lopez-Knowles E; Breast Cancer Research, Breakthrough Breast Cancer Research Centre, London, UK.
  • Dicks E; Academic Biochemistry, Royal Marsden Hospital, London, UK.
  • Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Sinnott-Armstrong NA; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Sallari RC; Department of Genetics, Stanford University School of Medicine, Stanford, California, USA.
  • Hillman KM; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Kaufmann S; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Sivakumaran H; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Moradi Marjaneh M; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Lee JS; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Hills M; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Jarosz M; Academic Biochemistry, Royal Marsden Hospital, London, UK.
  • Drury S; Breast Cancer Research, Breakthrough Breast Cancer Research Centre, London, UK.
  • Canisius S; Academic Biochemistry, Royal Marsden Hospital, London, UK.
  • Bolla MK; Breast Cancer Research, Breakthrough Breast Cancer Research Centre, London, UK.
  • Dennis J; Academic Biochemistry, Royal Marsden Hospital, London, UK.
  • Wang Q; Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
  • Hopper JL; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Southey MC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Broeks A; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Schmidt MK; Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.
  • Lophatananon A; Department of Pathology, University of Melbourne, Melbourne, Victoria, Australia.
  • Muir K; Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
  • Beckmann MW; Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
  • Fasching PA; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK.
  • Dos-Santos-Silva I; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK.
  • Peto J; Institute of Population Health, University of Manchester, Manchester, UK.
  • Sawyer EJ; Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-Nuremberg Metropolitan Region, Erlangen, Germany.
  • Tomlinson I; Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-Nuremberg Metropolitan Region, Erlangen, Germany.
  • Burwinkel B; Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
  • Marme F; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
  • Guénel P; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
  • Truong T; Research Oncology, Division of Cancer Studies, King's College London, Guy's Hospital, London, UK.
  • Bojesen SE; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Flyger H; Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.
  • González-Neira A; Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany.
  • Perez JI; Molecular Epidemiology Group, German Cancer Research Center, Heidelberg, Germany.
  • Anton-Culver H; National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany.
  • Eunjung L; Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.
  • Arndt V; Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France.
  • Brenner H; University Paris-Sud, Villejuif, France.
Nat Genet ; 48(4): 374-86, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26928228
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 6 / Neoplasias da Mama / Proteínas de Transporte / Proteínas de Ciclo Celular / Receptor alfa de Estrogênio Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Female / Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 6 / Neoplasias da Mama / Proteínas de Transporte / Proteínas de Ciclo Celular / Receptor alfa de Estrogênio Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Female / Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido