Evaluation of the eosinophil-to-lymphocyte ratio in pediatric patients with allergic rhinitis.
Am J Rhinol Allergy
; 30(2): e21-5, 2016.
Article
em En
| MEDLINE
| ID: mdl-26980381
ABSTRACT
BACKGROUND:
Allergic rhinitis is a type 1 hypersensitivity reaction of the nasal mucosa, the primary mediator of which is immunoglobulin E. Allergic rhinitis occurs in children and adolescents.OBJECTIVE:
This study examined the relationship between allergies and the eosinophil-to-lymphocyte ratio in children with allergic rhinitis with a positive skin-prick test. STUDYDESIGN:
This study was planned and performed as a case-control study.METHODS:
There were 695 patients who presented to our clinic who were enrolled in the study. Only group 4 fit the criteria for allergic rhinitis. Group 1 (nonsensitized asymptomatic [control group]), group 2 (nonsensitized symptomatic), group 3 (sensitized asymptomatic), and group 4 (sensitized symptomatic). The patients' allergy symptoms and skin test results were assessed and compared. The eosinophil-to-lymphocyte ratio for each patient was calculated. The eosinophil and lymphocyte counts and the eosinophil-to-lymphocyte ratio were calculated for each group.RESULTS:
The eosinophil-to-lymphocyte ratio and eosinophil counts in groups 3 and 4 were significantly higher (p < 0.001 and p < 0.001, respectively) than those in groups 1 and 2. The lymphocyte counts in groups 3 and 4 were significantly lower (p = 0.046) than those of groups 1 and 2.CONCLUSIONS:
The eosinophil-to-lymphocyte ratio may be used in conjunction with skin-prick testing in pediatric patients with allergic rhinitis. This parameter is inexpensive to measure and easy to use and calculate.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfócitos
/
Eosinófilos
/
Rinite Alérgica
/
Mucosa Nasal
Tipo de estudo:
Observational_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Am J Rhinol Allergy
Assunto da revista:
ALERGIA E IMUNOLOGIA
/
OTORRINOLARINGOLOGIA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Turquia