N-acetylgalactosamine glycans function in cancer cell adhesion to endothelial cells: A role for truncated O-glycans in metastatic mechanisms.

Bapu, Deepashree; Runions, John; Kadhim, Munira; Brooks, Susan Ann

Bapu, Deepashree; Runions, John; Kadhim, Munira; Brooks, Susan Ann.

Afiliação

Bapu D; Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3 0BP, UK.
Runions J; Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3 0BP, UK.
Kadhim M; Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3 0BP, UK.
Brooks SA; Department of Biological & Medical Sciences, Faculty of Health & Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford OX3 0BP, UK. Electronic address: sbrooks@brookes.ac.uk.

Cancer Lett ; 375(2): 367-374, 2016 Jun 01.

Article em En | MEDLINE | ID: mdl-26994652

Assuntos

Acetilgalactosamina/metabolismo; Neoplasias da Mama/metabolismo; Adesão Celular; Polissacarídeos/metabolismo; Antígenos Glicosídicos Associados a Tumores/metabolismo; Neoplasias da Mama/patologia; Membrana Celular/metabolismo; Células Endoteliais/metabolismo; Células Endoteliais/patologia; Feminino; Células Endoteliais da Veia Umbilical Humana; Humanos; Lectinas/metabolismo; Células MCF-7; Metástase Neoplásica

Palavras-chave

Helix pomatia agglutinin; Tn antigen; adhesion; glycosylation; metastasis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polissacarídeos / Acetilgalactosamina / Neoplasias da Mama / Adesão Celular Limite: Female / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2016 Tipo de documento: Article

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