PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM.

McCallum, Matthew; Tammam, Stephanie; Little, Dustin J; Robinson, Howard; Koo, Jason; Shah, Megha; Calmettes, Charles; Moraes, Trevor F; Burrows, Lori L; Howell, P Lynne

McCallum, Matthew; Tammam, Stephanie; Little, Dustin J; Robinson, Howard; Koo, Jason; Shah, Megha; Calmettes, Charles; Moraes, Trevor F; Burrows, Lori L; Howell, P Lynne.

Afiliação

McCallum M; From the Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, the Program in Molecular Structure and Function, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.
Tammam S; the Program in Molecular Structure and Function, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.
Little DJ; From the Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, the Program in Molecular Structure and Function, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.
Robinson H; the Photon Sciences Division, Brookhaven National Laboratory, Upton, New York 11973-5000, and.
Koo J; the Program in Molecular Structure and Function, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.
Shah M; From the Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Calmettes C; From the Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Moraes TF; From the Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Burrows LL; the Department of Biochemistry and Biomedical Sciences and the Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario L8N 3Z5, Canada burrowl@mcmaster.ca.
Howell PL; From the Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, the Program in Molecular Structure and Function, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada, howell@sickkids.ca.

J Biol Chem ; 291(21): 11003-15, 2016 May 20.

Article em En | MEDLINE | ID: mdl-27022027

Assuntos

Proteínas de Fímbrias/química; Proteínas de Fímbrias/metabolismo; Pseudomonas aeruginosa/metabolismo; Trifosfato de Adenosina/metabolismo; Sítios de Ligação/genética; Cristalografia por Raios X; Proteínas de Fímbrias/genética; Fímbrias Bacterianas/química; Fímbrias Bacterianas/classificação; Fímbrias Bacterianas/metabolismo; Modelos Moleculares; Complexos Multiproteicos/química; Complexos Multiproteicos/genética; Complexos Multiproteicos/metabolismo; Ligação Proteica; Domínios e Motivos de Interação entre Proteínas; Multimerização Proteica; Pseudomonas aeruginosa/genética; Pseudomonas aeruginosa/patogenicidade; Proteínas Recombinantes/química; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Solubilidade

Palavras-chave

PilM; PilN; Pseudomonas aeruginosa (P. aeruginosa); ligand-binding protein; protein chimera; type IV pili; x-ray crystallography

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Proteínas de Fímbrias Idioma: En Revista: J Biol Chem Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Canadá

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