Hepatic differentiation of human pluripotent stem cells in miniaturized format suitable for high-throughput screen.

Carpentier, Arnaud; Nimgaonkar, Ila; Chu, Virginia; Xia, Yuchen; Hu, Zongyi; Liang, T Jake

Carpentier, Arnaud; Nimgaonkar, Ila; Chu, Virginia; Xia, Yuchen; Hu, Zongyi; Liang, T Jake.

Afiliação

Carpentier A; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD 20892, USA. Electronic address: arnaud.carpentier@twincore.de.
Nimgaonkar I; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
Chu V; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
Xia Y; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
Hu Z; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
Liang TJ; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD 20892, USA. Electronic address: jakel@bdg10.niddk.nih.gov.

Stem Cell Res ; 16(3): 640-50, 2016 05.

Article em En | MEDLINE | ID: mdl-27062358

Assuntos

Hepatócitos/citologia; Células-Tronco Pluripotentes/citologia; Diferenciação Celular; Citocromo P-450 CYP3A/metabolismo; Fator 4 Nuclear de Hepatócito/metabolismo; Hepatócitos/metabolismo; Humanos; Microscopia de Fluorescência; Miniaturização; Fator 3 de Transcrição de Octâmero/metabolismo; Células-Tronco Pluripotentes/metabolismo; alfa-Fetoproteínas/metabolismo

Palavras-chave

384-Well plates; Hepatic differentiation; High-throughput assay; Pluripotent stem cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatócitos / Células-Tronco Pluripotentes Limite: Humans Idioma: En Revista: Stem Cell Res Ano de publicação: 2016 Tipo de documento: Article

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