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Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma.
Wei, Wei; Shin, Young Shik; Xue, Min; Matsutani, Tomoo; Masui, Kenta; Yang, Huijun; Ikegami, Shiro; Gu, Yuchao; Herrmann, Ken; Johnson, Dazy; Ding, Xiangming; Hwang, Kiwook; Kim, Jungwoo; Zhou, Jian; Su, Yapeng; Li, Xinmin; Bonetti, Bruno; Chopra, Rajesh; James, C David; Cavenee, Webster K; Cloughesy, Timothy F; Mischel, Paul S; Heath, James R; Gini, Beatrice.
Afiliação
  • Wei W; Division of Chemistry and Chemical Engineering, NanoSystems Biology Cancer Center, California Institute of Technology, Pasadena, CA 91125, USA; Department of Applied Physics and Materials Science, California Institute of Technology, Pasadena, CA 91125, USA; Department of Molecular and Medical Pharma
  • Shin YS; Division of Chemistry and Chemical Engineering, NanoSystems Biology Cancer Center, California Institute of Technology, Pasadena, CA 91125, USA; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Xue M; Division of Chemistry and Chemical Engineering, NanoSystems Biology Cancer Center, California Institute of Technology, Pasadena, CA 91125, USA.
  • Matsutani T; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Masui K; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Yang H; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Ikegami S; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Gu Y; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Herrmann K; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Johnson D; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Ding X; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Hwang K; Division of Chemistry and Chemical Engineering, NanoSystems Biology Cancer Center, California Institute of Technology, Pasadena, CA 91125, USA.
  • Kim J; Division of Chemistry and Chemical Engineering, NanoSystems Biology Cancer Center, California Institute of Technology, Pasadena, CA 91125, USA.
  • Zhou J; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Su Y; Division of Chemistry and Chemical Engineering, NanoSystems Biology Cancer Center, California Institute of Technology, Pasadena, CA 91125, USA.
  • Li X; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Bonetti B; Department of Neurological and Movement Sciences, University of Verona, Verona, 37134, Italy.
  • Chopra R; Celgene Corporation, San Diego, CA 92121, USA.
  • James CD; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Cavenee WK; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Cloughesy TF; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Mischel PS; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: pmischel@ucsd.edu.
  • Heath JR; Division of Chemistry and Chemical Engineering, NanoSystems Biology Cancer Center, California Institute of Technology, Pasadena, CA 91125, USA; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: heath@caltech.edu.
  • Gini B; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
Cancer Cell ; 29(4): 563-573, 2016 Apr 11.
Article em En | MEDLINE | ID: mdl-27070703
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Neoplasias Encefálicas / Protocolos de Quimioterapia Combinada Antineoplásica / Glioblastoma / Proteômica / Inibidores de Proteínas Quinases / Terapia de Alvo Molecular / Análise de Célula Única / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Neoplasias Encefálicas / Protocolos de Quimioterapia Combinada Antineoplásica / Glioblastoma / Proteômica / Inibidores de Proteínas Quinases / Terapia de Alvo Molecular / Análise de Célula Única / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article