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Identification of novel exonic mobile element insertions in epithelial ovarian cancers.
Hayano, Takahide; Yamada, Shiro; Hosomichi, Kazuyoshi; Nakaoka, Hirofumi; Yoshihara, Kosuke; Adachi, Sosuke; Kashima, Katsunori; Tanaka, Kenichi; Enomoto, Takayuki; Inoue, Ituro.
Afiliação
  • Hayano T; Division of Human Genetics, National Institute of Genetics , Mishima, Japan.
  • Yamada S; Division of Human Genetics, National Institute of Genetics , Mishima, Japan.
  • Hosomichi K; Division of Human Genetics, National Institute of Genetics , Mishima, Japan.
  • Nakaoka H; Division of Human Genetics, National Institute of Genetics , Mishima, Japan.
  • Yoshihara K; Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences , Niigata, Japan.
  • Adachi S; Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences , Niigata, Japan.
  • Kashima K; Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences , Niigata, Japan.
  • Tanaka K; Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan; Niigata Medical Center Hospital, Niigata, Japan.
  • Enomoto T; Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences , Niigata, Japan.
  • Inoue I; Division of Human Genetics, National Institute of Genetics , Mishima, Japan.
Hum Genome Var ; 2: 15030, 2015.
Article em En | MEDLINE | ID: mdl-27081539
Mobile elements comprise about half of the human genome. Three active mobile element families (L1, Alu, and SVA) possibly cause diseases such as cancer. We conducted mobile element insertion (MEI) profiling of 44 epithelial ovarian cancers using exome-sequencing data. We identified a total of 106 MEIs using the Mobster program, 8 of which were novel exonic MEIs.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Hum Genome Var Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Hum Genome Var Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão