Your browser doesn't support javascript.
loading
Four new diterpenoids isolated from the Euphorbia rapulum.
Liu, Xiao-Xue; Shang, Lei; Huang, Chao; Feng, Xue-Song; Li, Wen; Sha, Yi; Huang, Jian; Wang, Jin-Hui.
Afiliação
  • Liu XX; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Shang L; b School of Pharmacy , China Medical University , Shenyang 110122 , China.
  • Huang C; c School of Pharmacy , Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Feng XS; b School of Pharmacy , China Medical University , Shenyang 110122 , China.
  • Li W; c School of Pharmacy , Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Sha Y; c School of Pharmacy , Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Huang J; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Wang JH; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang 110016 , China.
J Asian Nat Prod Res ; 18(9): 823-30, 2016 Sep.
Article em En | MEDLINE | ID: mdl-27089930
ABSTRACT
Four new diterpenoids named 1-epi-9-hydroxydepressin (1), 1-epi-8-hydroxydepressin (2), 2,13,9-trihydroxy-labda-8(17),12(E),14-triene (3) and tagalsin I (4) were isolated from Euphorbia rapulum. The structures of these compounds were elucidated by means of various spectroscopic methods. All the isolated compounds were evaluated for cytotoxic activities against HepG2, MCF-7, and C6 cell lines, and compound 4 showed moderate selective activity against MCF-7 cell line with an IC50 value of 31.8 µM.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Euphorbia / Diterpenos Limite: Animals / Female / Humans Idioma: En Revista: J Asian Nat Prod Res Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Euphorbia / Diterpenos Limite: Animals / Female / Humans Idioma: En Revista: J Asian Nat Prod Res Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China