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Intervention with a caspase-1 inhibitor reduces obesity-associated hyperinsulinemia, non-alcoholic steatohepatitis and hepatic fibrosis in LDLR-/-.Leiden mice.
Morrison, M C; Mulder, P; Salic, K; Verheij, J; Liang, W; van Duyvenvoorde, W; Menke, A; Kooistra, T; Kleemann, R; Wielinga, P Y.
Afiliação
  • Morrison MC; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.
  • Mulder P; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • Salic K; Top Institute Food and Nutrition, Nieuwe Kanaal 9A, Wageningen, The Netherlands.
  • Verheij J; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.
  • Liang W; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.
  • van Duyvenvoorde W; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Menke A; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.
  • Kooistra T; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.
  • Kleemann R; TNO Triskelion, Zeist, The Netherlands.
  • Wielinga PY; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.
Int J Obes (Lond) ; 40(9): 1416-23, 2016 09.
Article em En | MEDLINE | ID: mdl-27121255

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Resistência à Insulina / Serpinas / Hepatopatia Gordurosa não Alcoólica / Hiperinsulinismo / Cirrose Hepática Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Int J Obes (Lond) Assunto da revista: METABOLISMO Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Resistência à Insulina / Serpinas / Hepatopatia Gordurosa não Alcoólica / Hiperinsulinismo / Cirrose Hepática Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Int J Obes (Lond) Assunto da revista: METABOLISMO Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda