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Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins.
Lee, Stanley Chun-Wei; Dvinge, Heidi; Kim, Eunhee; Cho, Hana; Micol, Jean-Baptiste; Chung, Young Rock; Durham, Benjamin H; Yoshimi, Akihide; Kim, Young Joon; Thomas, Michael; Lobry, Camille; Chen, Chun-Wei; Pastore, Alessandro; Taylor, Justin; Wang, Xujun; Krivtsov, Andrei; Armstrong, Scott A; Palacino, James; Buonamici, Silvia; Smith, Peter G; Bradley, Robert K; Abdel-Wahab, Omar.
Afiliação
  • Lee SC; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Dvinge H; Computational Biology Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Kim E; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Cho H; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Micol JB; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Chung YR; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Durham BH; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Yoshimi A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Kim YJ; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Thomas M; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Lobry C; H3 Biomedicine, Inc., Cambridge, Massachusetts, USA.
  • Chen CW; Institut National de la Santé et de la Recherche Medicale (INSERM) U1170, Institut Gustave Roussy, Villejuif, France.
  • Pastore A; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Taylor J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Wang X; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Krivtsov A; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Armstrong SA; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Palacino J; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Buonamici S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Smith PG; H3 Biomedicine, Inc., Cambridge, Massachusetts, USA.
  • Bradley RK; H3 Biomedicine, Inc., Cambridge, Massachusetts, USA.
  • Abdel-Wahab O; H3 Biomedicine, Inc., Cambridge, Massachusetts, USA.
Nat Med ; 22(6): 672-8, 2016 06.
Article em En | MEDLINE | ID: mdl-27135740
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Spliceossomos / Fatores de Processamento de Serina-Arginina Limite: Animals / Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Spliceossomos / Fatores de Processamento de Serina-Arginina Limite: Animals / Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos