Facile and ultrasensitive fluorescence sensor platform for tumor invasive biomaker ß-glucuronidase detection and inhibitor evaluation with carbon quantum dots based on inner-filter effect.

Lu, Shuaimin; Li, Guoliang; Lv, Zhengxian; Qiu, Nannan; Kong, Weiheng; Gong, Peiwei; Chen, Guang; Xia, Lian; Guo, Xiaoxi; You, Jinmao; Wu, Yongning

Lu, Shuaimin; Li, Guoliang; Lv, Zhengxian; Qiu, Nannan; Kong, Weiheng; Gong, Peiwei; Chen, Guang; Xia, Lian; Guo, Xiaoxi; You, Jinmao; Wu, Yongning.

Afiliação

Lu S; Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu 273165, People's Republic of China.
Li G; Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu 273165, People's Republic of China; Key Laboratories of Chemical Safety and Health, China National Center for Food Safety Risk Assessment, Beijing 100050, People's Republic of China. Electronic address: 612543
Lv Z; Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu 273165, People's Republic of China.
Qiu N; Key Laboratories of Chemical Safety and Health, China National Center for Food Safety Risk Assessment, Beijing 100050, People's Republic of China.
Kong W; Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu 273165, People's Republic of China.
Gong P; Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu 273165, People's Republic of China.
Chen G; Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu 273165, People's Republic of China.
Xia L; Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu 273165, People's Republic of China.
Guo X; Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu 273165, People's Republic of China.
You J; Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu 273165, People's Republic of China; Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810001, People's Republic of China. Electronic addre
Wu Y; Key Laboratories of Chemical Safety and Health, China National Center for Food Safety Risk Assessment, Beijing 100050, People's Republic of China. Electronic address: wuyongning@cfsa.net.cn.

Biosens Bioelectron ; 85: 358-362, 2016 Nov 15.

Article em En | MEDLINE | ID: mdl-27196253

Assuntos

Carbono/química; Inibidores Enzimáticos/farmacologia; Corantes Fluorescentes/química; Glucuronidase/antagonistas & inibidores; Glucuronidase/sangue; Pontos Quânticos/química; Espectrometria de Fluorescência/métodos; Técnicas Biossensoriais/métodos; Ensaios de Seleção de Medicamentos Antitumorais/métodos; Ensaios Enzimáticos/métodos; Glucuronidase/análise; Humanos; Limite de Detecção; Nitrogênio/química

Palavras-chave

Anti-tumor drug screening; Inner-filter effect; Nitrogen-doped carbon quantum dots; ß-glucuronidase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Fluorescência / Carbono / Pontos Quânticos / Inibidores Enzimáticos / Corantes Fluorescentes / Glucuronidase Tipo de estudo: Diagnostic_studies / Evaluation_studies / Screening_studies Limite: Humans Idioma: En Revista: Biosens Bioelectron Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2016 Tipo de documento: Article

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