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Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivatives.
Mowafy, Samar; Galanis, A; Doctor, Zainab M; Paranal, Raymond M; Lasheen, Deena S; Farag, Nahla A; Jänne, Pasi A; Abouzid, Khaled A M.
Afiliação
  • Mowafy S; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, 250 Longwood Ave., SGM 628, Boston, MA 02115, USA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Misr International
  • Galanis A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  • Doctor ZM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, 250 Longwood Ave., SGM 628, Boston, MA 02115, USA.
  • Paranal RM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  • Lasheen DS; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, 11566 Cairo, Egypt.
  • Farag NA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Misr International University, Km 28 Cairo-Ismailia Road (Ahmed Orabi District) Cairo, Egypt.
  • Jänne PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  • Abouzid KA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, 11566 Cairo, Egypt. Electronic address: khaled.abouzid@pharma.asu.edu.eg.
Bioorg Med Chem ; 24(16): 3501-12, 2016 08 15.
Article em En | MEDLINE | ID: mdl-27288180
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Receptores ErbB Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Receptores ErbB Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article