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The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.
Webster, Christopher P; Smith, Emma F; Bauer, Claudia S; Moller, Annekathrin; Hautbergue, Guillaume M; Ferraiuolo, Laura; Myszczynska, Monika A; Higginbottom, Adrian; Walsh, Matthew J; Whitworth, Alexander J; Kaspar, Brian K; Meyer, Kathrin; Shaw, Pamela J; Grierson, Andrew J; De Vos, Kurt J.
Afiliação
  • Webster CP; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • Smith EF; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • Bauer CS; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • Moller A; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • Hautbergue GM; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • Ferraiuolo L; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • Myszczynska MA; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • Higginbottom A; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • Walsh MJ; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • Whitworth AJ; Department of Biomedical Science, University of Sheffield, Sheffield, UK.
  • Kaspar BK; The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
  • Meyer K; The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
  • Shaw PJ; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • Grierson AJ; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK.
  • De Vos KJ; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience University of Sheffield, Sheffield, UK k.de_vos@sheffield.ac.uk.
EMBO J ; 35(15): 1656-76, 2016 08 01.
Article em En | MEDLINE | ID: mdl-27334615
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Proteínas / Fenômenos Fisiológicos Celulares / Proteínas rab1 de Ligação ao GTP / Peptídeos e Proteínas de Sinalização Intracelular / Proteína Homóloga à Proteína-1 Relacionada à Autofagia Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: EMBO J Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Proteínas / Fenômenos Fisiológicos Celulares / Proteínas rab1 de Ligação ao GTP / Peptídeos e Proteínas de Sinalização Intracelular / Proteína Homóloga à Proteína-1 Relacionada à Autofagia Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: EMBO J Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido