Enhanced binding of necrosis-targeting immunocytokine NHS-IL12 after local tumour irradiation in murine xenograft models.

Eckert, Franziska; Schmitt, Julia; Zips, Daniel; Krueger, Marcel A; Pichler, Bernd J; Gillies, Stephen D; Strittmatter, Wolfgang; Handgretinger, Rupert; Schilbach, Karin

Eckert, Franziska; Schmitt, Julia; Zips, Daniel; Krueger, Marcel A; Pichler, Bernd J; Gillies, Stephen D; Strittmatter, Wolfgang; Handgretinger, Rupert; Schilbach, Karin.

Afiliação

Eckert F; Department of Radiation Oncology, Eberhard Karls University Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany. franziska.eckert@med.uni-tuebingen.de.
Schmitt J; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tübingen, Röntgenweg 13, 72076, Tübingen, Germany.
Zips D; Department of Radiation Oncology, Eberhard Karls University Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.
Krueger MA; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tübingen, Röntgenweg 13, 72076, Tübingen, Germany.
Pichler BJ; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tübingen, Röntgenweg 13, 72076, Tübingen, Germany.
Gillies SD; Provenance Biopharmaceuticals, Carlisle, MA, USA.
Strittmatter W; Merck Serono R&D, Global Early Development, Merck KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany.
Handgretinger R; Department of General Pediatrics, Oncology/Hematology, Eberhard Karls University Tübingen, Hoppe-Seyler-Str. 1, 72076, Tübingen, Germany.
Schilbach K; Department of General Pediatrics, Oncology/Hematology, Eberhard Karls University Tübingen, Hoppe-Seyler-Str. 1, 72076, Tübingen, Germany.

Cancer Immunol Immunother ; 65(8): 1003-13, 2016 08.

Article em En | MEDLINE | ID: mdl-27376889

Assuntos

Imunoconjugados/imunologia; Neoplasias da Próstata/genética; Rabdomiossarcoma/genética; Animais; Linhagem Celular Tumoral; Modelos Animais de Doenças; Humanos; Masculino; Camundongos

Palavras-chave

ADC; Immunocytokine; Interleukin 12; Irradiation; MRI; PET

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Rabdomiossarcoma / Imunoconjugados Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cancer Immunol Immunother Assunto da revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha

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