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Folate-targeted amphiphilic cyclodextrin.siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and prolonged circulation in vivo.
Evans, James C; Malhotra, Meenakshi; Guo, Jianfeng; O'Shea, Joseph P; Hanrahan, Karen; O'Neill, Amanda; Landry, William D; Griffin, Brendan T; Darcy, Raphael; Watson, R William; O'Driscoll, Caitriona M.
Afiliação
  • Evans JC; Pharmacodelivery Group, School of Pharmacy, University College Cork, Cork, Ireland.
  • Malhotra M; Pharmacodelivery Group, School of Pharmacy, University College Cork, Cork, Ireland.
  • Guo J; Pharmacodelivery Group, School of Pharmacy, University College Cork, Cork, Ireland.
  • O'Shea JP; Pharmacodelivery Group, School of Pharmacy, University College Cork, Cork, Ireland.
  • Hanrahan K; UCD Conway Institute of Biomolecular and Biomedical Research, UCD School of Medicine, University College Dublin, Dublin, Ireland.
  • O'Neill A; UCD Conway Institute of Biomolecular and Biomedical Research, UCD School of Medicine, University College Dublin, Dublin, Ireland.
  • Landry WD; Pharmacodelivery Group, School of Pharmacy, University College Cork, Cork, Ireland.
  • Griffin BT; Pharmacodelivery Group, School of Pharmacy, University College Cork, Cork, Ireland.
  • Darcy R; Pharmacodelivery Group, School of Pharmacy, University College Cork, Cork, Ireland.
  • Watson RW; UCD Conway Institute of Biomolecular and Biomedical Research, UCD School of Medicine, University College Dublin, Dublin, Ireland.
  • O'Driscoll CM; Pharmacodelivery Group, School of Pharmacy, University College Cork, Cork, Ireland. Electronic address: caitriona.odriscoll@ucc.ie.
Nanomedicine ; 12(8): 2341-2351, 2016 11.
Article em En | MEDLINE | ID: mdl-27389146
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / RNA Interferente Pequeno / Nanopartículas Limite: Humans / Male Idioma: En Revista: Nanomedicine Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Irlanda
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / RNA Interferente Pequeno / Nanopartículas Limite: Humans / Male Idioma: En Revista: Nanomedicine Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Irlanda