A Cytolethal Distending Toxin Variant from Aggregatibacter actinomycetemcomitans with an Aberrant CdtB That Lacks the Conserved Catalytic Histidine 160.

Obradovic, Davor; Gaspersic, Rok; Caserman, Simon; Leonardi, Adrijana; Jamnik, Maja; Podlesek, Zdravko; Seme, Katja; Anderluh, Gregor; Krizaj, Igor; Macek, Peter; Butala, Matej

Obradovic, Davor; Gaspersic, Rok; Caserman, Simon; Leonardi, Adrijana; Jamnik, Maja; Podlesek, Zdravko; Seme, Katja; Anderluh, Gregor; Krizaj, Igor; Macek, Peter; Butala, Matej.

Afiliação

Obradovic D; Department of Biology, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia.
Gaspersic R; Department of Oral Medicine and Periodontology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Caserman S; Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia.
Leonardi A; Department of Molecular and Biomedical Sciences, Jozef Stefan Institute, Ljubljana, Slovenia.
Jamnik M; Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia.
Podlesek Z; Department of Biology, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia.
Seme K; Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Anderluh G; Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia.
Krizaj I; Department of Molecular and Biomedical Sciences, Jozef Stefan Institute, Ljubljana, Slovenia.
Macek P; Department of Chemistry and Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia.
Butala M; Department of Biology, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia.

PLoS One ; 11(7): e0159231, 2016.

Article em En | MEDLINE | ID: mdl-27414641

Assuntos

Aggregatibacter actinomycetemcomitans/genética; Aggregatibacter actinomycetemcomitans/patogenicidade; Toxinas Bacterianas/genética; Adulto; Aggregatibacter actinomycetemcomitans/isolamento & purificação; Sequência de Aminoácidos; Toxinas Bacterianas/química; Toxinas Bacterianas/toxicidade; Periodontite Crônica/etiologia; Periodontite Crônica/microbiologia; Sequência Conservada; Genes Bacterianos; Variação Genética; Células HeLa; Histidina/química; Humanos; Células Jurkat; Modelos Moleculares; Óperon; Conformação Proteica; Deleção de Sequência; Virulência/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Toxinas Bacterianas / Aggregatibacter actinomycetemcomitans Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Eslovênia

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