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Splenomegaly, elevated alkaline phosphatase and mutations in the SRSF2/ASXL1/RUNX1 gene panel are strong adverse prognostic markers in patients with systemic mastocytosis.
Jawhar, M; Schwaab, J; Hausmann, D; Clemens, J; Naumann, N; Henzler, T; Horny, H-P; Sotlar, K; Schoenberg, S O; Cross, N C P; Fabarius, A; Hofmann, W-K; Valent, P; Metzgeroth, G; Reiter, A.
Afiliação
  • Jawhar M; Department of Hematology and Oncology, University Medical Centre Mannheim, Mannheim, Germany.
  • Schwaab J; Department of Hematology and Oncology, University Medical Centre Mannheim, Mannheim, Germany.
  • Hausmann D; Institute of Clinical Radiology and Nuclear Medicine, University Medical Centre Mannheim, Mannheim, Germany.
  • Clemens J; Department of Hematology and Oncology, University Medical Centre Mannheim, Mannheim, Germany.
  • Naumann N; Department of Hematology and Oncology, University Medical Centre Mannheim, Mannheim, Germany.
  • Henzler T; Institute of Clinical Radiology and Nuclear Medicine, University Medical Centre Mannheim, Mannheim, Germany.
  • Horny HP; Institute of Pathology, Ludwig-Maximilians-University, Munich, Germany.
  • Sotlar K; Institute of Pathology, Ludwig-Maximilians-University, Munich, Germany.
  • Schoenberg SO; Institute of Clinical Radiology and Nuclear Medicine, University Medical Centre Mannheim, Mannheim, Germany.
  • Cross NC; Wessex Regional Genetics Laboratory, Salisbury, UK.
  • Fabarius A; Faculty of Medicine, University of Southampton, Southampton, UK.
  • Hofmann WK; Department of Hematology and Oncology, University Medical Centre Mannheim, Mannheim, Germany.
  • Valent P; Department of Hematology and Oncology, University Medical Centre Mannheim, Mannheim, Germany.
  • Metzgeroth G; Department of Internal Medicine I, Division of Hematology and Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
  • Reiter A; Department of Hematology and Oncology, University Medical Centre Mannheim, Mannheim, Germany.
Leukemia ; 30(12): 2342-2350, 2016 12.
Article em En | MEDLINE | ID: mdl-27416984
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Esplenomegalia / Mastocitose Sistêmica / Fosfatase Alcalina / Subunidade alfa 2 de Fator de Ligação ao Core / Fatores de Processamento de Serina-Arginina / Mutação Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Esplenomegalia / Mastocitose Sistêmica / Fosfatase Alcalina / Subunidade alfa 2 de Fator de Ligação ao Core / Fatores de Processamento de Serina-Arginina / Mutação Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha