Effects of the Nrf2 Protein Modulator Salvianolic Acid A Alone or Combined with Metformin on Diabetes-associated Macrovascular and Renal Injury.

Wu, Ping; Yan, Yu; Ma, Lin-Lin; Hou, Bi-Yu; He, Yang-Yang; Zhang, Li; Niu, Zi-Ran; Song, Jun-Ke; Pang, Xiao-Cong; Yang, Xiu-Ying; Du, Guan-Hua

Wu, Ping; Yan, Yu; Ma, Lin-Lin; Hou, Bi-Yu; He, Yang-Yang; Zhang, Li; Niu, Zi-Ran; Song, Jun-Ke; Pang, Xiao-Cong; Yang, Xiu-Ying; Du, Guan-Hua.

Afiliação

Wu P; From the Institute of Materia Medica and.
Yan Y; From the Institute of Materia Medica and.
Ma LL; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050 and.
Hou BY; From the Institute of Materia Medica and.
He YY; From the Institute of Materia Medica and the State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Beijing 100037, China.
Zhang L; From the Institute of Materia Medica and.
Niu ZR; From the Institute of Materia Medica and.
Song JK; From the Institute of Materia Medica and.
Pang XC; From the Institute of Materia Medica and.
Yang XY; From the Institute of Materia Medica and.
Du GH; From the Institute of Materia Medica and dugh@imm.ac.cn.

J Biol Chem ; 291(42): 22288-22301, 2016 Oct 14.

Article em En | MEDLINE | ID: mdl-27417135

Assuntos

Alcenos/farmacologia; Diabetes Mellitus Experimental/tratamento farmacológico; Angiopatias Diabéticas/tratamento farmacológico; Nefropatias Diabéticas/tratamento farmacológico; Metformina/farmacologia; Fator 2 Relacionado a NF-E2/metabolismo; Polifenóis/farmacologia; Animais; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Experimental/patologia; Angiopatias Diabéticas/metabolismo; Nefropatias Diabéticas/metabolismo; Glutationa Peroxidase/metabolismo; Heme Oxigenase-1/metabolismo; Masculino; Proteínas de Membrana/metabolismo; Camundongos; Camundongos Endogâmicos ICR; NAD(P)H Desidrogenase (Quinona)/metabolismo; Glutationa Peroxidase GPX1

Palavras-chave

Nuclear factor 2 (erythroid-derived 2-like factor) (NFE2L2) (Nrf2); diabetes; diabetic macrovascular injury; diabetic nephropathy; metformin; oxidative stress; salvianolic acid A

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Experimental / Angiopatias Diabéticas / Nefropatias Diabéticas / Alcenos / Fator 2 Relacionado a NF-E2 / Polifenóis / Metformina Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2016 Tipo de documento: Article

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