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ALS/FTD-associated FUS activates GSK-3ß to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.
Stoica, Radu; Paillusson, Sébastien; Gomez-Suaga, Patricia; Mitchell, Jacqueline C; Lau, Dawn Hw; Gray, Emma H; Sancho, Rosa M; Vizcay-Barrena, Gema; De Vos, Kurt J; Shaw, Christopher E; Hanger, Diane P; Noble, Wendy; Miller, Christopher Cj.
Afiliação
  • Stoica R; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Paillusson S; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Gomez-Suaga P; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Mitchell JC; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Lau DH; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Gray EH; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Sancho RM; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Vizcay-Barrena G; Centre for Ultrastructural Imaging, King's College London, London, UK.
  • De Vos KJ; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Shaw CE; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Hanger DP; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Noble W; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Miller CC; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK chris.miller@kcl.ac.uk.
EMBO Rep ; 17(9): 1326-42, 2016 09.
Article em En | MEDLINE | ID: mdl-27418313
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Fosfatases / Proteínas Mitocondriais / Proteína FUS de Ligação a RNA / Proteínas de Transporte Vesicular / Retículo Endoplasmático / Demência Frontotemporal / Glicogênio Sintase Quinase 3 beta / Esclerose Lateral Amiotrófica / Mitocôndrias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: EMBO Rep Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Fosfatases / Proteínas Mitocondriais / Proteína FUS de Ligação a RNA / Proteínas de Transporte Vesicular / Retículo Endoplasmático / Demência Frontotemporal / Glicogênio Sintase Quinase 3 beta / Esclerose Lateral Amiotrófica / Mitocôndrias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: EMBO Rep Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido