Gingival granulomatosis with polyangiitis (Wegener's granulomatosis) as a primary manifestation of the disease.
Aust Dent J
; 62(1): 102-106, 2017 Mar.
Article
em En
| MEDLINE
| ID: mdl-27439744
ABSTRACT
Granulomatosis with polyangiitis (GPA) is a potentially lethal disease characterized by systemic necrotizing vasculitis, which affects small- and medium-sized blood vessels and is often associated with serum cytoplasmic antineutrophil cytoplasmic antibody. The upper and lower respiratory tract and kidney are the most involved sites, but oral lesions can be identified in 6-13% of the cases, whereas in only 2% of the cases, oral manifestations represent the first signal of the disease usually as gingival swellings or unspecific ulcerations. Without treatment, the mainstay of which is the combination of immunosuppressants and systemic corticosteroids, GPA may run a fatal course. In this report we describe an original case of GPA affecting a 75-year-old female patient referred to our service due to a gingival swelling with 3-month duration. Although the patient was correctly diagnosed and promptly treated, she died 3 months after the initial diagnosis.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Granulomatose com Poliangiite
/
Corticosteroides
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Doenças da Gengiva
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Imunossupressores
Tipo de estudo:
Diagnostic_studies
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Prognostic_studies
Limite:
Aged
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Female
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Humans
Idioma:
En
Revista:
Aust Dent J
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Brasil