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Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma.
van Lith, Sanne A M; Navis, Anna C; Lenting, Krissie; Verrijp, Kiek; Schepens, Jan T G; Hendriks, Wiljan J A J; Schubert, Nil A; Venselaar, Hanka; Wevers, Ron A; van Rooij, Arno; Wesseling, Pieter; Molenaar, Remco J; van Noorden, Cornelis J F; Pusch, Stefan; Tops, Bastiaan; Leenders, William P J.
Afiliação
  • van Lith SA; Department of Pathology, Radboudumc, Nijmegen, The Netherlands.
  • Navis AC; Department of Pathology, Radboudumc, Nijmegen, The Netherlands.
  • Lenting K; Department of Pathology, Radboudumc, Nijmegen, The Netherlands.
  • Verrijp K; Department of Pathology, Radboudumc, Nijmegen, The Netherlands.
  • Schepens JT; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, The Netherlands.
  • Hendriks WJ; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, The Netherlands.
  • Schubert NA; Department of Pathology, Radboudumc, Nijmegen, The Netherlands.
  • Venselaar H; Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, The Netherlands.
  • Wevers RA; Translational Metabolic Laboratory, Department Laboratory Medicine, Radboudumc, Nijmegen, The Netherlands.
  • van Rooij A; Translational Metabolic Laboratory, Department Laboratory Medicine, Radboudumc, Nijmegen, The Netherlands.
  • Wesseling P; Department of Pathology, Radboudumc, Nijmegen, The Netherlands.
  • Molenaar RJ; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
  • van Noorden CJ; Department of Cell Biology and Histology, Academic Medical Center, Amsterdam, The Netherlands.
  • Pusch S; Department of Cell Biology and Histology, Academic Medical Center, Amsterdam, The Netherlands.
  • Tops B; Clinical Cooperation Unit Neuropathology, German Cancer Center (DKFZ), Heidelberg, Germany.
  • Leenders WP; Department of Pathology, Radboudumc, Nijmegen, The Netherlands.
Sci Rep ; 6: 30486, 2016 07 27.
Article em En | MEDLINE | ID: mdl-27460417
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Astrocitoma / Neoplasias Encefálicas / Isocitrato Desidrogenase / Mutação Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Astrocitoma / Neoplasias Encefálicas / Isocitrato Desidrogenase / Mutação Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda