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Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases.
Chan, Mun Chiang; Ilott, Nicholas E; Schödel, Johannes; Sims, David; Tumber, Anthony; Lippl, Kerstin; Mole, David R; Pugh, Christopher W; Ratcliffe, Peter J; Ponting, Chris P; Schofield, Christopher J.
Afiliação
  • Chan MC; From the Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3TA, the Centre for Cellular and Molecular Physiology, University of Oxford, Oxford OX3 7BN.
  • Ilott NE; the Computational Genomics Analysis and Training Programme, MRC Functional Genomics Unit Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, and.
  • Schödel J; the Centre for Cellular and Molecular Physiology, University of Oxford, Oxford OX3 7BN.
  • Sims D; the Computational Genomics Analysis and Training Programme, MRC Functional Genomics Unit Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, and.
  • Tumber A; the Target Discovery Institute, University of Oxford, Oxford OX3 7FZ, United Kingdom.
  • Lippl K; From the Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3TA.
  • Mole DR; the Centre for Cellular and Molecular Physiology, University of Oxford, Oxford OX3 7BN.
  • Pugh CW; the Centre for Cellular and Molecular Physiology, University of Oxford, Oxford OX3 7BN.
  • Ratcliffe PJ; the Centre for Cellular and Molecular Physiology, University of Oxford, Oxford OX3 7BN.
  • Ponting CP; the Computational Genomics Analysis and Training Programme, MRC Functional Genomics Unit Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, and.
  • Schofield CJ; From the Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford OX1 3TA, christopher.schofield@chem.ox.ac.uk.
J Biol Chem ; 291(39): 20661-73, 2016 09 23.
Article em En | MEDLINE | ID: mdl-27502280
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Regulação Enzimológica da Expressão Gênica / Prolina Dioxigenases do Fator Induzível por Hipóxia Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Regulação Enzimológica da Expressão Gênica / Prolina Dioxigenases do Fator Induzível por Hipóxia Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2016 Tipo de documento: Article