Review of Critical Issues in the Pathogenesis of Atopic Dermatitis.
Semin Cutan Med Surg
; 35(5 Suppl): S89-91, 2016 Jun.
Article
em En
| MEDLINE
| ID: mdl-27525507
ABSTRACT
About a decade age, loss-of-function mutations in the filaggrin molecule were first implicated in the pathogenesis of ichthyosis vulgaris and, subsequently, of atopic dermatitis and other atopic diseases. Since then, intensive study of the role of filaggrin null mutations have led to other milestones in understanding the pathologic pathways in these diseases, including the initiation, maintenance, and promotion of the disease processes. The result has been new and emerging clinical and pharmacologic strategies for early identification of and intervention in atopic diseases. Semin Cutan Med Surg 35(supp5)S89-S91.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dermatite Atópica
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
En
Revista:
Semin Cutan Med Surg
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Irlanda