Resolution advances in cryo-EM enable application to drug discovery.

Subramaniam, Sriram; Earl, Lesley A; Falconieri, Veronica; Milne, Jacqueline Ls; Egelman, Edward H

Subramaniam, Sriram; Earl, Lesley A; Falconieri, Veronica; Milne, Jacqueline Ls; Egelman, Edward H.

Afiliação

Subramaniam S; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: ss1@nih.gov.
Earl LA; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Falconieri V; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Milne JL; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Egelman EH; University of Virginia, Charlottesville, VA 22908, USA.

Curr Opin Struct Biol ; 41: 194-202, 2016 12.

Article em En | MEDLINE | ID: mdl-27552081

Assuntos

Microscopia Crioeletrônica/métodos; Descoberta de Drogas/métodos; Animais; Humanos; Ligantes; Razão Sinal-Ruído; Bibliotecas de Moléculas Pequenas/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microscopia Crioeletrônica / Descoberta de Drogas Limite: Animals / Humans Idioma: En Revista: Curr Opin Struct Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article

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