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A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease.
Kauppila, Johanna H K; Baines, Holly L; Bratic, Ana; Simard, Marie-Lune; Freyer, Christoph; Mourier, Arnaud; Stamp, Craig; Filograna, Roberta; Larsson, Nils-Göran; Greaves, Laura C; Stewart, James B.
Afiliação
  • Kauppila JHK; Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne 50931, Germany.
  • Baines HL; Newcastle University LLHW Centre for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Bratic A; Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne 50931, Germany.
  • Simard ML; Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne 50931, Germany.
  • Freyer C; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden.
  • Mourier A; Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne 50931, Germany.
  • Stamp C; Newcastle University LLHW Centre for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Filograna R; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden.
  • Larsson NG; Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne 50931, Germany; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden. Electronic address: larsson@age.mpg.de.
  • Greaves LC; Newcastle University LLHW Centre for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; Wellcome Trust Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Stewart JB; Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne 50931, Germany. Electronic address: jstewart@age.mpg.de.
Cell Rep ; 16(11): 2980-2990, 2016 09 13.
Article em En | MEDLINE | ID: mdl-27626666

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Doenças Mitocondriais / Mutação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Doenças Mitocondriais / Mutação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha