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Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.
Harlow, Matt L; Maloney, Nichole; Roland, Joseph; Guillen Navarro, Maria Jose; Easton, Matthew K; Kitchen-Goosen, Susan M; Boguslawski, Elissa A; Madaj, Zachary B; Johnson, Ben K; Bowman, Megan J; D'Incalci, Maurizio; Winn, Mary E; Turner, Lisa; Hostetter, Galen; Galmarini, Carlos María; Aviles, Pablo M; Grohar, Patrick J.
Afiliação
  • Harlow ML; Department of Cancer Biology, Vanderbilt University, Nashville, Tennessee.
  • Maloney N; Department of Pediatrics, Vanderbilt University, Nashville, Tennessee.
  • Roland J; Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, Tennessee.
  • Guillen Navarro MJ; PharmaMar, Madrid, Spain.
  • Easton MK; Van Andel Research Institute, Grand Rapids, Michigan.
  • Kitchen-Goosen SM; Van Andel Research Institute, Grand Rapids, Michigan.
  • Boguslawski EA; Van Andel Research Institute, Grand Rapids, Michigan.
  • Madaj ZB; Van Andel Research Institute, Grand Rapids, Michigan.
  • Johnson BK; Van Andel Research Institute, Grand Rapids, Michigan.
  • Bowman MJ; Van Andel Research Institute, Grand Rapids, Michigan.
  • D'Incalci M; IRCCS - Instituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
  • Winn ME; Van Andel Research Institute, Grand Rapids, Michigan.
  • Turner L; Van Andel Research Institute, Grand Rapids, Michigan.
  • Hostetter G; Van Andel Research Institute, Grand Rapids, Michigan.
  • Galmarini CM; PharmaMar, Madrid, Spain.
  • Aviles PM; PharmaMar, Madrid, Spain.
  • Grohar PJ; Department of Pediatrics, Vanderbilt University, Nashville, Tennessee. patrick.grohar@vai.org.
Cancer Res ; 76(22): 6657-6668, 2016 11 15.
Article em En | MEDLINE | ID: mdl-27697767
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Camptotecina / Proteínas de Fusão Oncogênica / Proteínas Oncogênicas / Proteína EWS de Ligação a RNA / Proteína Proto-Oncogênica c-fli-1 Limite: Animals / Female / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Camptotecina / Proteínas de Fusão Oncogênica / Proteínas Oncogênicas / Proteína EWS de Ligação a RNA / Proteína Proto-Oncogênica c-fli-1 Limite: Animals / Female / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2016 Tipo de documento: Article