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Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.
Villar-Piqué, Anna; Lopes da Fonseca, Tomás; Sant'Anna, Ricardo; Szegö, Éva Mónika; Fonseca-Ornelas, Luis; Pinho, Raquel; Carija, Anita; Gerhardt, Ellen; Masaracchia, Caterina; Abad Gonzalez, Enrique; Rossetti, Giulia; Carloni, Paolo; Fernández, Claudio O; Foguel, Debora; Milosevic, Ira; Zweckstetter, Markus; Ventura, Salvador; Outeiro, Tiago Fleming.
Afiliação
  • Villar-Piqué A; Department of Neurodegeneration and Restorative Research, University Medical Centre Göttingen, 37073 Goettingen, Germany.
  • Lopes da Fonseca T; Department of Neurodegeneration and Restorative Research, University Medical Centre Göttingen, 37073 Goettingen, Germany.
  • Sant'Anna R; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, 21941-901 Rio de Janeiro, Brazil; Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain; Departament de Bioquímica i Biologia Molecular, Facultat de Bi
  • Szegö ÉM; Department of Neurodegeneration and Restorative Research, University Medical Centre Göttingen, 37073 Goettingen, Germany.
  • Fonseca-Ornelas L; Max-Planck-Institut für Biophysikalische Chemie, 37077 Goettingen, Germany.
  • Pinho R; Department of Neurodegeneration and Restorative Research, University Medical Centre Göttingen, 37073 Goettingen, Germany.
  • Carija A; Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain.
  • Gerhardt E; Department of Neurodegeneration and Restorative Research, University Medical Centre Göttingen, 37073 Goettingen, Germany.
  • Masaracchia C; Department of Neurodegeneration and Restorative Research, University Medical Centre Göttingen, 37073 Goettingen, Germany.
  • Abad Gonzalez E; Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, Forschungszentrum Jülich, 52425 Jülich, Germany; German Research School for Simulation Sciences, Forschungszentrum Jülich, 52425 Jülich, Germany.
  • Rossetti G; Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, Forschungszentrum Jülich, 52425 Jülich, Germany; Department of Oncology, Hematology, and Stem Cell Transplantation, Medical School, Rheinisch-Westfälische Technische Hochschule Aachen
  • Carloni P; Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, Forschungszentrum Jülich, 52425 Jülich, Germany.
  • Fernández CO; Max Planck Laboratory for Structural Biology, Chemistry, and Molecular Biophysics of Rosario, Universidad Nacional de Rosario, Ocampo y Esmeralda, S2002LRK Rosario, Argentina; Instituto de Investigaciones para el Descubrimiento de Fármacos de Rosario UNR-Consejo Nacional de Investigaciones Científic
  • Foguel D; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, 21941-901 Rio de Janeiro, Brazil.
  • Milosevic I; European Neuroscience Institute, 37077 Goettingen, Germany.
  • Zweckstetter M; Max-Planck-Institut für Biophysikalische Chemie, 37077 Goettingen, Germany; Deutsches Zentrum für Neurodegenerative Erkrankungen, 37075 Goettingen, Germany; Department of Neurology, University Medicine Göttingen, 37073 Goettingen, Germany; Center for Nanoscale Microscopy and Molecular Physiology of
  • Ventura S; Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain; Departament de Bioquímica i Biologia Molecular, Facultat de Biociències, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain.
  • Outeiro TF; Department of Neurodegeneration and Restorative Research, University Medical Centre Göttingen, 37073 Goettingen, Germany; Max Planck Institute for Experimental Medicine, Goettingen, Germany touteir@gwdg.de.
Proc Natl Acad Sci U S A ; 113(42): E6506-E6515, 2016 10 18.
Article em En | MEDLINE | ID: mdl-27708160
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Meio Ambiente / Alfa-Sinucleína / Agregação Patológica de Proteínas / Agregados Proteicos Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Meio Ambiente / Alfa-Sinucleína / Agregação Patológica de Proteínas / Agregados Proteicos Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha