Comparison of the Adipose and Luminal Mammary Gland Compartment as Orthotopic Inoculation Sites in a 4T1-Based Immunocompetent Preclinical Model for Triple-Negative Breast Cancer.

Steenbrugge, Jonas; Breyne, Koen; Denies, Sofie; Dekimpe, Melissa; Demeyere, Kristel; De Wever, Olivier; Vermeulen, Peter; Van Laere, Steven; Sanders, Niek N; Meyer, Evelyne

Steenbrugge, Jonas; Breyne, Koen; Denies, Sofie; Dekimpe, Melissa; Demeyere, Kristel; De Wever, Olivier; Vermeulen, Peter; Van Laere, Steven; Sanders, Niek N; Meyer, Evelyne.

Afiliação

Steenbrugge J; Laboratory of Biochemistry, Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium. Jonas.Steenbrugge@UGent.be.
Breyne K; Translational Cancer Research Unit Antwerp, Center for Oncological Research, General Hospital Sint-Augustinus, Wilrijk, Belgium. Jonas.Steenbrugge@UGent.be.
Denies S; Laboratory of Biochemistry, Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Dekimpe M; Laboratory of Gene Therapy, Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Demeyere K; Laboratory of Biochemistry, Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
De Wever O; Laboratory of Gene Therapy, Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Vermeulen P; Laboratory of Biochemistry, Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Van Laere S; Department of Radiation Oncology and Experimental Cancer Research, Laboratory of Experimental Cancer Research, Ghent University, Ghent, Belgium.
Sanders NN; Translational Cancer Research Unit Antwerp, Center for Oncological Research, General Hospital Sint-Augustinus, Wilrijk, Belgium.
Meyer E; Translational Cancer Research Unit Antwerp, Center for Oncological Research, General Hospital Sint-Augustinus, Wilrijk, Belgium.

J Mammary Gland Biol Neoplasia ; 21(3-4): 113-122, 2016 12.

Article em En | MEDLINE | ID: mdl-27714576

Assuntos

Tecido Adiposo/patologia; Carcinogênese/patologia; Neoplasias Mamárias Experimentais/patologia; Neoplasias de Mama Triplo Negativas/patologia; Tecido Adiposo/metabolismo; Animais; Biomarcadores Tumorais/metabolismo; Carcinogênese/metabolismo; Linhagem Celular Tumoral; Modelos Animais de Doenças; Feminino; Humanos; Lactação/metabolismo; Neoplasias Hepáticas/metabolismo; Neoplasias Hepáticas/patologia; Neoplasias Hepáticas/secundário; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patologia; Neoplasias Pulmonares/secundário; Neoplasias Mamárias Experimentais/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Obesidade/metabolismo; Obesidade/patologia; Neoplasias de Mama Triplo Negativas/metabolismo

Palavras-chave

4T1 immunocompetent preclinical model; Adipose and luminal compartment; Chitinase 3-like 1; Lipocalin 2; Orthotopic inoculation; Triple-negative breast cancer

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Neoplasias de Mama Triplo Negativas / Carcinogênese / Neoplasias Mamárias Experimentais Limite: Animals / Female / Humans Idioma: En Revista: J Mammary Gland Biol Neoplasia Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Bélgica

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