Phyllanthus urinaria's Inhibition of Human Osteosarcoma Xenografts Growth in Mice is Associated with Modulation of Mitochondrial Fission/Fusion Machinery.

Huang, Sheng-Teng; Huang, Chao-Chun; Sheen, Jer-Ming; Lin, Tsu-Kung; Liao, Pei-Lin; Huang, Wen-Liang; Wang, Pei-Wen; Liou, Chia-Wei; Chuang, Jiin-Haur

Huang, Sheng-Teng; Huang, Chao-Chun; Sheen, Jer-Ming; Lin, Tsu-Kung; Liao, Pei-Lin; Huang, Wen-Liang; Wang, Pei-Wen; Liou, Chia-Wei; Chuang, Jiin-Haur.

Afiliação

Huang ST; * Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan.
Huang CC; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan.
Sheen JM; Division of General Surgery, Ministry of Health and Welfare Pingtung Hospital, Pingtung, Taiwan.
Lin TK; § Department of Chinese Medicine and Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Liao PL; ** Department of Neurology and Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Huang WL; ** Department of Neurology and Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Wang PW; ** Department of Neurology and Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Liou CW; ¶ Department of Internal Medicine and Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Chuang JH; ** Department of Neurology and Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Am J Chin Med ; 44(7): 1507-1523, 2016.

Article em En | MEDLINE | ID: mdl-27776427

Assuntos

Antineoplásicos Fitogênicos; Apoptose/efeitos dos fármacos; Apoptose/genética; Proliferação de Células/efeitos dos fármacos; Proliferação de Células/genética; Dinâmica Mitocondrial/efeitos dos fármacos; Dinâmica Mitocondrial/genética; Osteonecrose/genética; Osteonecrose/patologia; Osteossarcoma/genética; Osteossarcoma/patologia; Phyllanthus/química; Fitoterapia; Extratos Vegetais/farmacologia; Extratos Vegetais/uso terapêutico; Animais; DNA Nucleotidilexotransferase/metabolismo; Xenoenxertos; Humanos; Antígeno Ki-67/metabolismo; Camundongos Endogâmicos NOD; Camundongos SCID; Transplante de Neoplasias; Extratos Vegetais/isolamento & purificação; Antígeno Nuclear de Célula em Proliferação/metabolismo

Palavras-chave

Angiogenesis; Apoptosis; Mitochondrial Dynamics; Phyllanthus urinaria

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteonecrose / Extratos Vegetais / Osteossarcoma / Apoptose / Phyllanthus / Proliferação de Células / Dinâmica Mitocondrial / Fitoterapia / Antineoplásicos Fitogênicos Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Am J Chin Med Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Taiwan

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